Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 31 Researches
7.7
USERS' SCORE
Good
Based on 6 Reviews
8.2
Supplement Facts
Serving Size:  1 vegan softgel
Amount Per Serving
%DV
Calories
5
_
Total Fat
0.5 g
<1%‡
Microalgae Oil (40% DHA)which typically provides:
500 mg
*
DHA (Docosahexaenoic Acid) [Ω-3]
200 mg
*

Top Medical Research Studies

We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.

For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
We investigated how eicosapentaenoic acid (EPA) affects heart rhythm, particularly in the context of high-fat diets. In our study, mice were divided into two groups: one received a high-fat diet, while the other’s diet was supplemented with EPA for eight weeks.

We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
Read More
9
High-dose omega-3 improves heart function
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.

Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.

However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More

Most Useful Reviews

7.5
Improves heart health
66 people found this helpful
I have not consumed meat, fish, or seafood since 2008, making Omega-3 and vitamin B-12 essential staples from iHerb. Omega-3 offers several benefits: it enhances metabolism, supports heart health by lowering blood pressure and cholesterol, and improves joint function. It positively affects the brain and memory, boosts immunity, and elevates mood. Insufficient Omega-3 can lead to skin issues, fatigue, and even heart disease. Including Omega-3-rich foods in my diet or opting for this product ensures I remain healthy. Wishing everyone health and love! 💗
Read More
9
Heart health improvement
1 people found this helpful
My dad has taken this supplement for years, benefiting his heart health significantly. It's a great source of Omega-3.
Read More
9
Maintains heart health
1 people found this helpful
Deva Omega 3 DHA is an excellent vegan supplement. These tablets are easy to consume and effective. Omega-3 fatty acids support heart, eye, and nervous system health. Since taking these, I’ve noticed improvements in my health overall. They are gluten-free and vegan-friendly, making them a great choice for heart health.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 31 Researches
7.7
  • All Researches
We analyzed the impact of different fatty acid-derived acylcarnitines on heart health. The study found that saturated and monounsaturated acylcarnitines, especially trans-elaidoylcarnitine, significantly impaired heart function and mitochondrial activity, leading to cardiotoxicity.

In contrast, omega-3-derived acylcarnitines, like eicosapentaenoylcarnitine and docosahexaenoylcarnitine, were found to be safe, having little to no negative effect on heart function and cell viability. Overall, this research suggests that omega-3 fatty acids may be a safer option for those facing cardiac challenges.
Read More
9
High-dose omega-3 improves heart function
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.

Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.

However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More
We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.

For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
9
Omega-3 benefits African Americans’ heart health
We observed that the role of omega-3 fatty acids in heart health showed promising results specifically for African Americans. By comparing matched groups from the VITAL trial, we found that omega-3 supplementation significantly reduced the risk of myocardial infarction in African Americans, while no such benefit was seen in non-Hispanic whites.

This suggests that genetic or lifestyle factors may influence the effectiveness of these supplements. Our findings highlight the importance of further research to better understand how race affects responses to omega-3 supplementation.
Read More
9
DHA linked to reduced heart risks
We explored how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, might help reduce the risk of heart disease, specifically sudden cardiac death (SCD) and cardiovascular mortality. Our investigation drew on data from ten prospective cohort studies involving over 310,000 participants and covered an average follow-up of nearly nine years.

The results were promising. We observed that higher levels of omega-3 fatty acids, including DHA, in the blood were associated with a lower risk of adverse heart events. Specifically, individuals with elevated levels of DHA displayed a notable reduced risk for both SCD and overall cardiovascular mortality when compared to those with lower levels.

This correlation highlights DHA's potential role in heart health, making it an important focus for anyone looking to improve their cardiovascular wellness. Our findings suggest that increasing DHA intake could serve as a proactive step in protecting against serious heart conditions.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Improves heart health
66 people found this helpful
I have not consumed meat, fish, or seafood since 2008, making Omega-3 and vitamin B-12 essential staples from iHerb. Omega-3 offers several benefits: it enhances metabolism, supports heart health by lowering blood pressure and cholesterol, and improves joint function. It positively affects the brain and memory, boosts immunity, and elevates mood. Insufficient Omega-3 can lead to skin issues, fatigue, and even heart disease. Including Omega-3-rich foods in my diet or opting for this product ensures I remain healthy. Wishing everyone health and love! 💗
Read More
9
Heart health improvement
1 people found this helpful
My dad has taken this supplement for years, benefiting his heart health significantly. It's a great source of Omega-3.
Read More
9
Maintains heart health
1 people found this helpful
Deva Omega 3 DHA is an excellent vegan supplement. These tablets are easy to consume and effective. Omega-3 fatty acids support heart, eye, and nervous system health. Since taking these, I’ve noticed improvements in my health overall. They are gluten-free and vegan-friendly, making them a great choice for heart health.
Read More
7.5
Aids heart function
1 people found this helpful
Finding vegetarian Omega-3 is challenging, but iHerb has come through. The dosage here is lower than ideal, so I supplement to reach 1000mg, which is the recommended amount for heart disease prevention. While Omega-3 protects cells, its efficacy depends on individual health conditions. Excess can negatively impact health, so moderation is key. I find this product excellent, with easy-to-swallow capsules.
Read More
7.5
Heart health improvement
I appreciate this vegan, non-fish Omega-3 source. I take it to enhance heart health, reduce inflammation, and lower cholesterol. It’s a quality product without undesirable ingredients like silicon dioxide and magnesium stearate.
Read More

Frequently Asked Questions

9
Heart health improvement
1 people found this helpful
My dad has taken this supplement for years, benefiting his heart health significantly. It's a great source of Omega-3.
9
Maintains heart health
1 people found this helpful
Deva Omega 3 DHA is an excellent vegan supplement. These tablets are easy to consume and effective. Omega-3 fatty acids support heart, eye, and nervous system health. Since taking these, I’ve noticed improvements in my health overall. They are gluten-free and vegan-friendly, making them a great choice for heart health.
7.5
Aids heart function
1 people found this helpful
Finding vegetarian Omega-3 is challenging, but iHerb has come through. The dosage here is lower than ideal, so I supplement to reach 1000mg, which is the recommended amount for heart disease prevention. While Omega-3 protects cells, its efficacy depends on individual health conditions. Excess can negatively impact health, so moderation is key. I find this product excellent, with easy-to-swallow capsules.
7.5
Improves heart health
66 people found this helpful
I have not consumed meat, fish, or seafood since 2008, making Omega-3 and vitamin B-12 essential staples from iHerb. Omega-3 offers several benefits: it enhances metabolism, supports heart health by lowering blood pressure and cholesterol, and improves joint function. It positively affects the brain and memory, boosts immunity, and elevates mood. Insufficient Omega-3 can lead to skin issues, fatigue, and even heart disease. Including Omega-3-rich foods in my diet or opting for this product ensures I remain healthy. Wishing everyone health and love! 💗
7.5
Heart health improvement
I appreciate this vegan, non-fish Omega-3 source. I take it to enhance heart health, reduce inflammation, and lower cholesterol. It’s a quality product without undesirable ingredients like silicon dioxide and magnesium stearate.
We investigated how eicosapentaenoic acid (EPA) affects heart rhythm, particularly in the context of high-fat diets. In our study, mice were divided into two groups: one received a high-fat diet, while the other’s diet was supplemented with EPA for eight weeks.

We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
4
Omega-3 deficiency linked to heart disease
We examined how a diet deficient in omega-3 fatty acids correlates with the burden of ischemic heart disease (IHD) from 1990 to 2021.

The findings reveal a concerning association: low omega-3 intake contributed to millions of disability-adjusted life years and deaths globally, indicating a notable impact on heart health.

While some regions, like South Asia, faced a higher burden, the overall trend shows that promoting healthier diets rich in omega-3 could be pivotal in reducing heart disease risk.
9
High-dose omega-3 improves heart function
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.

Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.

However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
We analyzed data from the UK Biobank involving 117,702 participants to understand how docosahexaenoic acid (DHA), a type of omega-3 fatty acid found in marine sources, impacts long-term heart health and overall mortality. Over an impressive follow-up period of about 12.7 years, we explored the relationship between plasma DHA levels and various mortality causes, including cardiovascular disease and cancer.

Our findings revealed that individuals with higher DHA levels had significantly lower risks of dying from all causes, including heart disease and cancer. Specifically, comparing those with the lowest DHA levels to those with the highest, we noted a remarkable 21% reduction in all-cause mortality, along with a 21% decrease in deaths attributed to cardiovascular diseases.

This provides compelling evidence that increasing DHA intake could play a key role in supporting heart health and longevity. The results help substantiate the idea that DHA is beneficial, suggesting we might want to consider it as part of a healthy diet for better heart health and a longer life.
8
Omega-3 reduces heart disease risk
We explored the effectiveness of icosapent ethyl, a form of omega-3 fish oil, in lowering heart disease rates among high-risk patients with varying cholesterol levels.

In a clinical trial with statin-treated individuals who had elevated triglycerides, it was found that those taking icosapent ethyl experienced significantly fewer cardiovascular events compared to those on a placebo.

Notably, this benefit was seen regardless of their baseline low-density lipoprotein cholesterol (LDL-C) levels, indicating positive outcomes even for patients with well-controlled cholesterol.

References

  1. Liepinsh E, Gukalova B, Krims-Davis K, Kuka J, Leduskrasta A, et al. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors. 2025;51:e70014. doi:10.1002/biof.70014
  2. Xu J, Peng T, Kong L, Wei N. A global analysis of the burden of ischemic heart disease attributable to diet low in ω-3 fatty acids between 1990 and 2021. BMC Cardiovasc Disord. 2025;25:188. doi:10.1186/s12872-025-04620-z
  3. Horii K, Ono K, Sumi T, Higashihara M, Zaima N, et al. Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice. J Physiol Sci. 2025;75:100014. doi:10.1016/j.jphyss.2025.100014
  4. Dawczynski C, Drobner T, Weidauer T, Schlattmann P, Kiehntopf M, et al. Reduction of cardiovascular risk factors by the diet - Evaluation of the MoKaRi concept by a parallel-designed randomized study. Lipids Health Dis. 2025;24:88. doi:10.1186/s12944-025-02500-1
  5. Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. doi:10.1161/JAHA.124.038656
  6. Tseng PT, Zeng BY, Hsu CW, Liang CS, Stubbs B, et al. The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis. Adv Nutr. 2025;16:100366. doi:10.1016/j.advnut.2025.100366
  7. Hemmati R, Bahrami Zanjanbar D, Shishesaz MI, Soleimani A, Yari T. The impact of Omega-3 supplementation on arrhythmia reduction in acute coronary syndrome patients: a randomized clinical trial. J Complement Integr Med. 2025;22:173. doi:10.1515/jcim-2024-0427
  8. Wang Y, Wu G, Wang Y, Rehman A, Yu L, et al. Recent developments, challenges, and prospects of dietary omega-3 PUFA-fortified foods: Focusing on their effects on cardiovascular diseases. Food Chem. 2025;470:142498. doi:10.1016/j.foodchem.2024.142498
  9. Jawad MA, O'Keefe JH, Tintle N, O'Keefe EL, Franco WG, et al. Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities. Mayo Clin Proc. 2024;99:1895. doi:10.1016/j.mayocp.2024.08.007
  10. Lee YQ, Tan KH, Chong MF. Biomarkers of PUFA and cardiovascular risk factors and events in healthy Asian populations: a systematic review. Br J Nutr. 2024;132:1474. doi:10.1017/S0007114524002708
  11. Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. doi:10.1038/s44319-024-00271-x
  12. Ryuno Y, Kobayashi JI, Fujimoto Y, Dotare T, Matsue Y, et al. Effect of an Enteral Formula Enriched With ω-3 Fatty Acids, Carnitine, and Vitamin D on Body Weight, Heart Weight, and Blood Biochemical Parameters in a Dahl Rat Heart Failure Model. J Cardiovasc Pharmacol. 2024;84:590. doi:10.1097/FJC.0000000000001637
  13. Sun S, Hara A, Johnstone L, Hallmark B, Watkins JC, et al. Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation. Nutrients. 2024;16. doi:10.3390/nu16172933
  14. Ahmadi M, Askari VR, Shahri B, Mousavi Noghab SM, Jarahi L, et al. Omega-3 fatty acids effectively mitigate high-sensitivity C-reactive protein (hs-CRP) biomarker of inflammation in acute myocardial infarction patients: a randomized, double-blind, placebo-controlled clinical trial. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:881. doi:10.1007/s00210-024-03330-1
  15. Chen HC, Tai CJ, Huang JY, Kuo TA, Huang YD, et al. Associations of fish oil with cardiovascular disease events: results from the Taiwan longitudinal study in aging. BMC Public Health. 2024;24:1979. doi:10.1186/s12889-024-19512-8
  16. Yu Y, Gao M, Xu H. Ginger Extract and Omega-3 Fatty Acids Supplementation: A Promising Strategy to Improve Diabetic Cardiomyopathy. Physiol Res. 2024;73:351.
  17. Hamaya R, Cook NR, Sesso HD, Buring JE, Manson JE. A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events. Am J Clin Nutr. 2025. doi:10.1016/j.ajcnut.2025.02.028
  18. Kim JY, Kong SYJ, Jung E, Cho YS. Omega-3 Fatty Acids as Potential Predictors of Sudden Cardiac Death and Cardiovascular Mortality: A Systematic Review and Meta-Analysis. J Clin Med. 2024;14. doi:10.3390/jcm14010026
  19. O'Keefe EL, O'Keefe JH, Abuissa H, Metzinger M, Murray E, et al. Omega-3 and Risk of atrial fibrillation: Vagally-mediated double-edged sword. Prog Cardiovasc Dis. 2024. doi:10.1016/j.pcad.2024.11.003
  20. Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. doi:10.3389/fnut.2024.1423228
  21. Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, et al. Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis. Eur J Prev Cardiol. 2025;32:233. doi:10.1093/eurjpc/zwae315
  22. Amangurbanova M, Daher R, Asbeutah AA, Vemuri B, Mirza H, et al. Higher epicardial adipose tissue volume is associated with higher coronary fatty plaque volume and is regulated by waist circumference but not EPA+DHA supplementation. J Clin Lipidol. 2024;18:e773. doi:10.1016/j.jacl.2024.06.006
  23. Lv L, Guo Y, Zheng Z, Li B. Blood metabolites mediate effects of breakfast skipping on heart failure via Mendelian randomization analysis. Sci Rep. 2024;14:18957. doi:10.1038/s41598-024-69874-7
  24. Wang Y, Yang B, Wang C. The association between fatty acids and atherosclerotic diseases: A mendelian randomization study. Clin Nutr ESPEN. 2024;63:447. doi:10.1016/j.clnesp.2024.06.018
  25. Tian S, Guo T, Qian F, Qiu Z, Lu Q, et al. Fish Oil, Plasma n-3 PUFAs, and Risk of Macro- and Microvascular Complications among Individuals with Type 2 Diabetes. J Clin Endocrinol Metab. 2024. doi:10.1210/clinem/dgae482
  26. Asbeutah AA, Daher R, Malik A, Hariri E, Alfaddagh A, et al. The Effect of Eicosapentaenoic and Docosahexaenoic Acid Supplementation on Coronary Artery Calcium Progression in Subjects With Diabetes and Coronary Artery Disease: A Secondary Analysis of a Randomized Trial. Am J Cardiol. 2024;225:98. doi:10.1016/j.amjcard.2024.06.001
  27. Dinu M, Sofi F, Lotti S, Colombini B, Mattioli AV, et al. Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis. Eur J Prev Cardiol. 2024;31:1863. doi:10.1093/eurjpc/zwae184
  28. Braun TS, Drobner T, Kipp K, Kiehntopf M, Schlattmann P, et al. Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study. Nutrients. 2024;16. doi:10.3390/nu16091261
  29. O'Keefe EL, O'Keefe JH, Tintle NL, Westra J, Albuisson L, et al. Circulating Docosahexaenoic Acid and Risk of All-Cause and Cause-Specific Mortality. Mayo Clin Proc. 2024;99:534. doi:10.1016/j.mayocp.2023.11.026
  30. Zeinalabedini M, Ladaninezhad M, Mobarakeh KA, Hoshiar-Rad A, Shekari S, et al. Association of dietary fats with ischemic heart disease (IHD): a case-control study. J Health Popul Nutr. 2024;43:19. doi:10.1186/s41043-023-00489-w
  31. Rennemo J, Berge K, Yousaf MN, Eriksen TB, Welde E, et al. An Atypical Course of Cardiomyopathy Syndrome (CMS) in Farmed Atlantic Salmon () Fed a Clinical Nutrition Diet. Microorganisms. 2023;12. doi:10.3390/microorganisms12010026
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