We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.
For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
8
EPA lowers heart rhythm problems
Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice.
We investigated how eicosapentaenoic acid (EPA) affects heart rhythm, particularly in the context of high-fat diets. In our study, mice were divided into two groups: one received a high-fat diet, while the other’s diet was supplemented with EPA for eight weeks.
We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
Read More
9
High-dose omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.
Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.
However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More
Most Useful Reviews
7.5
Improves heart health
66 people found this helpful
I have not consumed meat, fish, or seafood since 2008, making Omega-3 and vitamin B-12 essential staples from iHerb. Omega-3 offers several benefits: it enhances metabolism, supports heart health by lowering blood pressure and cholesterol, and improves joint function. It positively affects the brain and memory, boosts immunity, and elevates mood. Insufficient Omega-3 can lead to skin issues, fatigue, and even heart disease. Including Omega-3-rich foods in my diet or opting for this product ensures I remain healthy. Wishing everyone health and love! 💗
Read More
9
Heart health improvement
1 people found this helpful
My dad has taken this supplement for years, benefiting his heart health significantly. It's a great source of Omega-3.
Read More
9
Maintains heart health
1 people found this helpful
Deva Omega 3 DHA is an excellent vegan supplement. These tablets are easy to consume and effective. Omega-3 fatty acids support heart, eye, and nervous system health. Since taking these, I’ve noticed improvements in my health overall. They are gluten-free and vegan-friendly, making them a great choice for heart health.
We analyzed the impact of different fatty acid-derived acylcarnitines on heart health. The study found that saturated and monounsaturated acylcarnitines, especially trans-elaidoylcarnitine, significantly impaired heart function and mitochondrial activity, leading to cardiotoxicity.
In contrast, omega-3-derived acylcarnitines, like eicosapentaenoylcarnitine and docosahexaenoylcarnitine, were found to be safe, having little to no negative effect on heart function and cell viability. Overall, this research suggests that omega-3 fatty acids may be a safer option for those facing cardiac challenges.
Read More
9
High-dose omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.
Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.
However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More
9
Omega-3 reduces heart disease risk
Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities.
We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.
For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
9
Omega-3 benefits African Americans’ heart health
Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation.
We observed that the role of omega-3 fatty acids in heart health showed promising results specifically for African Americans. By comparing matched groups from the VITAL trial, we found that omega-3 supplementation significantly reduced the risk of myocardial infarction in African Americans, while no such benefit was seen in non-Hispanic whites.
This suggests that genetic or lifestyle factors may influence the effectiveness of these supplements. Our findings highlight the importance of further research to better understand how race affects responses to omega-3 supplementation.
Read More
9
DHA linked to reduced heart risks
Omega-3 Fatty Acids as Potential Predictors of Sudden Cardiac Death and Cardiovascular Mortality: A Systematic Review and Meta-Analysis.
We explored how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, might help reduce the risk of heart disease, specifically sudden cardiac death (SCD) and cardiovascular mortality. Our investigation drew on data from ten prospective cohort studies involving over 310,000 participants and covered an average follow-up of nearly nine years.
The results were promising. We observed that higher levels of omega-3 fatty acids, including DHA, in the blood were associated with a lower risk of adverse heart events. Specifically, individuals with elevated levels of DHA displayed a notable reduced risk for both SCD and overall cardiovascular mortality when compared to those with lower levels.
This correlation highlights DHA's potential role in heart health, making it an important focus for anyone looking to improve their cardiovascular wellness. Our findings suggest that increasing DHA intake could serve as a proactive step in protecting against serious heart conditions.
I have not consumed meat, fish, or seafood since 2008, making Omega-3 and vitamin B-12 essential staples from iHerb. Omega-3 offers several benefits: it enhances metabolism, supports heart health by lowering blood pressure and cholesterol, and improves joint function. It positively affects the brain and memory, boosts immunity, and elevates mood. Insufficient Omega-3 can lead to skin issues, fatigue, and even heart disease. Including Omega-3-rich foods in my diet or opting for this product ensures I remain healthy. Wishing everyone health and love! 💗
Read More
9
Heart health improvement
1 people found this helpful
My dad has taken this supplement for years, benefiting his heart health significantly. It's a great source of Omega-3.
Read More
9
Maintains heart health
1 people found this helpful
Deva Omega 3 DHA is an excellent vegan supplement. These tablets are easy to consume and effective. Omega-3 fatty acids support heart, eye, and nervous system health. Since taking these, I’ve noticed improvements in my health overall. They are gluten-free and vegan-friendly, making them a great choice for heart health.
Read More
7.5
Aids heart function
1 people found this helpful
Finding vegetarian Omega-3 is challenging, but iHerb has come through. The dosage here is lower than ideal, so I supplement to reach 1000mg, which is the recommended amount for heart disease prevention. While Omega-3 protects cells, its efficacy depends on individual health conditions. Excess can negatively impact health, so moderation is key. I find this product excellent, with easy-to-swallow capsules.
Read More
7.5
Heart health improvement
I appreciate this vegan, non-fish Omega-3 source. I take it to enhance heart health, reduce inflammation, and lower cholesterol. It’s a quality product without undesirable ingredients like silicon dioxide and magnesium stearate.
Heart disease refers to a range of conditions that affect the heart's function and overall health. This umbrella term includes various cardiovascular issues such as coronary artery disease, which is caused by the buildup of plaque in the arteries; heart rhythm problems (arrhythmias); and heart defects present at birth (congenital heart defects). Additionally, heart disease encompasses conditions related to the heart muscle, such as cardiomyopathy, and the heart's valves, which might not open or close properly. The effects of heart disease can be significant, impacting not only physical health but also quality of life, making prevention and timely medical intervention crucial.
Several risk factors contribute to the development of heart disease, including high blood pressure, high cholesterol levels, diabetes, obesity, poor diet, physical inactivity, and smoking. Genetics also play a role, as heart disease can run in families. To mitigate the risks, healthcare professionals typically recommend lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and avoiding tobacco use. For those already diagnosed with heart disease, treatment options can vary widely, ranging from lifestyle modifications to medications and, in severe cases, surgical interventions. Understanding the nature of heart disease and its risk factors is an essential step toward prevention and effective management.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
Omega-3 fish oil has long been touted for its potential heart health benefits, and there is a growing body of research that supports its positive role in cardiovascular health. Omega-3 fatty acids—primarily EPA and DHA, found in fish oil—are known to help reduce inflammation, lower triglyceride levels, and may improve arterial function. Studies suggest that regular consumption of omega-3s can lead to a modest reduction in the risk of heart disease, particularly for those with existing cardiovascular conditions or elevated risk factors.
However, it's essential to note that while omega-3 fish oil can be beneficial, it should not be seen as a standalone treatment for heart disease. It's most effective when used in conjunction with a heart-healthy lifestyle, which includes a balanced diet, regular exercise, and other preventative measures. As always, it's recommended to consult with a healthcare professional before starting any new supplement regimen, especially for individuals with existing health issues or those on medication. Keep in mind that the effectiveness can vary from person to person, depending on individual health profiles and dietary needs.
Based on user reviews, the time it takes to see results from Omega-3 supplements for heart disease can vary significantly among individuals. Some users, like one who mentions their father experiencing significant heart health benefits after years of taking the supplement, suggest that long-term use can lead to noticeable improvements in heart health Read Review. Other reviewers note overall health improvements after starting the supplement, although they do not specify a timeline Read Review.
However, it’s essential to note that the effectiveness of Omega-3 supplements can greatly depend on individual health conditions and dietary habits. One user indicates that they find their supplement effective but also mention that while Omega-3 is beneficial, proper dosage is crucial for optimal heart disease prevention Read Review. As a general guideline, consistency in using the supplement plays a key role, and incorporating it as part of a broader healthy lifestyle may yield the best results over time.
Scientific research increasingly supports the role of omega-3 fatty acids in promoting heart health, particularly in reducing the risk of heart disease. Various studies have shown that omega-3s, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), can have beneficial effects such as lowering triglyceride levels, improving lipid profiles, and even mitigating arrhythmias. For instance, one trial indicated that patients receiving EPA experienced significantly fewer heart rhythm issues compared to those not supplemented [3]. Moreover, in studies involving over 25,000 participants, dailyomega-3 supplementation has been correlated with a lower risk of major cardiovascular events, highlighting its potential role in heart disease prevention [2].
In addition to the above, evidence suggests that patients with existing heart conditions may benefit from omega-3 supplementation. Research involving randomized trials has reported significant improvements in heart function among individuals taking high doses of omega-3 over extended periods [6]. Furthermore, those with higher levels of DHA in their system displayed reduced mortality rates related to cardiovascular diseases, reinforcing the notion that omega-3 fatty acids could be crucial for heart disease management [29]. While much of this evidence points toward the health benefits of omega-3 supplements, further research is essential to fully elucidate their effects, especially in diverse populations.
Based on user reviews, many users have reported significant improvements in various health aspects after incorporating Omega-3 supplements into their routine. For instance, one user mentions that they have experienced benefits in metabolism, heart health, joint function, brain function, and mood enhancement, highlighting Omega-3's broad range of positive effects Read Review. Another reviewer notes that their father has seen substantial heart health benefits after years of consistent use of the supplement, which reinforces the notion of long-term positive outcomes related to heart wellness Read Review.
Multiple users have also indicated overall health improvements after starting the supplement, with specific mentions of enhanced heart, eye, and nervous system health Read Review. Additionally, users are appreciating that this vegan Omega-3 can assist in reducing inflammation and harmful cholesterol levels, further supporting heart health and overall wellness Read Review. However, it's essential to note that individual results can vary significantly, influenced by personal health circumstances and adherence to recommended dosages Read Review.
Based on user reviews, many individuals have reported positive experiences when combining Omega-3 with other supplements or dietary strategies aimed at managing heart disease. Users highlight Omega-3's role in enhancing heart health, with some noting its effectiveness in lowering blood pressure and cholesterol levels Read Review. One reviewer mentions adjusting their dosage of Omega-3 to reach the recommended amount for heart disease prevention, indicating that supplementation can be tailored to meet personal health needs Read Review.
Moreover, users appreciate the compatibility of this vegan Omega-3 with other health supplements, reinforcing its benefits without the undesirable ingredients often found in other products Read Review. Others have shared that they maintain a diet rich in Omega-3 while ensuring to include a variety of other healthful nutrients, which further supports heart health and wellness Read Review. Overall, the reviews suggest that Omega-3 supplements can be effectively integrated into a broader health regimen for those seeking to mitigate heart disease.
According to research, the optimal dose of omega-3 fish oil for treating heart disease typically falls within the range of 2000 to 4000 mg daily. A comprehensive analysis of 14 randomized controlled trials, which included over 9,000 participants, indicated that this high-dose regimen significantly improved heart function and overall outcomes for patients managing heart failure. Notably, this level of supplementation was associated with beneficial heart metrics, such as enhanced ejection fraction and important markers of heart performance, when taken over an extended period of at least one year [6].
Furthermore, other studies corroborate the benefits of higher omega-3 intake. For example, a clinical trial evaluating the effects of icosapent ethyl—a specific form of omega-3 fish oil—on high-risk individuals showed that those supplementing experienced significantly fewer cardiovascular events than those on a placebo, regardless of their baseline cholesterol levels [5]. These findings highlight not only the therapeutic potential of omega-3 fatty acids for heart health but also underline the importance of adhering to these enhanced dosages to maximize their cardioprotective effects.
9
Heart health improvement
1 people found this helpful
My dad has taken this supplement for years, benefiting his heart health significantly. It's a great source of Omega-3.
9
Maintains heart health
1 people found this helpful
Deva Omega 3 DHA is an excellent vegan supplement. These tablets are easy to consume and effective. Omega-3 fatty acids support heart, eye, and nervous system health. Since taking these, I’ve noticed improvements in my health overall. They are gluten-free and vegan-friendly, making them a great choice for heart health.
7.5
Aids heart function
1 people found this helpful
Finding vegetarian Omega-3 is challenging, but iHerb has come through. The dosage here is lower than ideal, so I supplement to reach 1000mg, which is the recommended amount for heart disease prevention. While Omega-3 protects cells, its efficacy depends on individual health conditions. Excess can negatively impact health, so moderation is key. I find this product excellent, with easy-to-swallow capsules.
7.5
Improves heart health
66 people found this helpful
I have not consumed meat, fish, or seafood since 2008, making Omega-3 and vitamin B-12 essential staples from iHerb. Omega-3 offers several benefits: it enhances metabolism, supports heart health by lowering blood pressure and cholesterol, and improves joint function. It positively affects the brain and memory, boosts immunity, and elevates mood. Insufficient Omega-3 can lead to skin issues, fatigue, and even heart disease. Including Omega-3-rich foods in my diet or opting for this product ensures I remain healthy. Wishing everyone health and love! 💗
7.5
Heart health improvement
I appreciate this vegan, non-fish Omega-3 source. I take it to enhance heart health, reduce inflammation, and lower cholesterol. It’s a quality product without undesirable ingredients like silicon dioxide and magnesium stearate.
8
EPA lowers heart rhythm problems
Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice.
We investigated how eicosapentaenoic acid (EPA) affects heart rhythm, particularly in the context of high-fat diets. In our study, mice were divided into two groups: one received a high-fat diet, while the other’s diet was supplemented with EPA for eight weeks.
We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
4
Omega-3 deficiency linked to heart disease
A global analysis of the burden of ischemic heart disease attributable to diet low in ω-3 fatty acids between 1990 and 2021.
We examined how a diet deficient in omega-3 fatty acids correlates with the burden of ischemic heart disease (IHD) from 1990 to 2021.
The findings reveal a concerning association: low omega-3 intake contributed to millions of disability-adjusted life years and deaths globally, indicating a notable impact on heart health.
While some regions, like South Asia, faced a higher burden, the overall trend shows that promoting healthier diets rich in omega-3 could be pivotal in reducing heart disease risk.
9
High-dose omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.
Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.
However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
8
DHA reduces heart disease mortality
Circulating Docosahexaenoic Acid and Risk of All-Cause and Cause-Specific Mortality.
We analyzed data from the UK Biobank involving 117,702 participants to understand how docosahexaenoic acid (DHA), a type of omega-3 fatty acid found in marine sources, impacts long-term heart health and overall mortality. Over an impressive follow-up period of about 12.7 years, we explored the relationship between plasma DHA levels and various mortality causes, including cardiovascular disease and cancer.
Our findings revealed that individuals with higher DHA levels had significantly lower risks of dying from all causes, including heart disease and cancer. Specifically, comparing those with the lowest DHA levels to those with the highest, we noted a remarkable 21% reduction in all-cause mortality, along with a 21% decrease in deaths attributed to cardiovascular diseases.
This provides compelling evidence that increasing DHA intake could play a key role in supporting heart health and longevity. The results help substantiate the idea that DHA is beneficial, suggesting we might want to consider it as part of a healthy diet for better heart health and a longer life.
8
Omega-3 reduces heart disease risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
We explored the effectiveness of icosapent ethyl, a form of omega-3 fish oil, in lowering heart disease rates among high-risk patients with varying cholesterol levels.
In a clinical trial with statin-treated individuals who had elevated triglycerides, it was found that those taking icosapent ethyl experienced significantly fewer cardiovascular events compared to those on a placebo.
Notably, this benefit was seen regardless of their baseline low-density lipoprotein cholesterol (LDL-C) levels, indicating positive outcomes even for patients with well-controlled cholesterol.
References
Liepinsh E, Gukalova B, Krims-Davis K, Kuka J, Leduskrasta A, et al. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors. 2025;51:e70014. doi:10.1002/biof.70014
Xu J, Peng T, Kong L, Wei N. A global analysis of the burden of ischemic heart disease attributable to diet low in ω-3 fatty acids between 1990 and 2021. BMC Cardiovasc Disord. 2025;25:188. doi:10.1186/s12872-025-04620-z
Horii K, Ono K, Sumi T, Higashihara M, Zaima N, et al. Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice. J Physiol Sci. 2025;75:100014. doi:10.1016/j.jphyss.2025.100014
Dawczynski C, Drobner T, Weidauer T, Schlattmann P, Kiehntopf M, et al. Reduction of cardiovascular risk factors by the diet - Evaluation of the MoKaRi concept by a parallel-designed randomized study. Lipids Health Dis. 2025;24:88. doi:10.1186/s12944-025-02500-1
Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. doi:10.1161/JAHA.124.038656
Tseng PT, Zeng BY, Hsu CW, Liang CS, Stubbs B, et al. The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis. Adv Nutr. 2025;16:100366. doi:10.1016/j.advnut.2025.100366
Hemmati R, Bahrami Zanjanbar D, Shishesaz MI, Soleimani A, Yari T. The impact of Omega-3 supplementation on arrhythmia reduction in acute coronary syndrome patients: a randomized clinical trial. J Complement Integr Med. 2025;22:173. doi:10.1515/jcim-2024-0427
Wang Y, Wu G, Wang Y, Rehman A, Yu L, et al. Recent developments, challenges, and prospects of dietary omega-3 PUFA-fortified foods: Focusing on their effects on cardiovascular diseases. Food Chem. 2025;470:142498. doi:10.1016/j.foodchem.2024.142498
Jawad MA, O'Keefe JH, Tintle N, O'Keefe EL, Franco WG, et al. Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities. Mayo Clin Proc. 2024;99:1895. doi:10.1016/j.mayocp.2024.08.007
Lee YQ, Tan KH, Chong MF. Biomarkers of PUFA and cardiovascular risk factors and events in healthy Asian populations: a systematic review. Br J Nutr. 2024;132:1474. doi:10.1017/S0007114524002708
Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. doi:10.1038/s44319-024-00271-x
Ryuno Y, Kobayashi JI, Fujimoto Y, Dotare T, Matsue Y, et al. Effect of an Enteral Formula Enriched With ω-3 Fatty Acids, Carnitine, and Vitamin D on Body Weight, Heart Weight, and Blood Biochemical Parameters in a Dahl Rat Heart Failure Model. J Cardiovasc Pharmacol. 2024;84:590. doi:10.1097/FJC.0000000000001637
Sun S, Hara A, Johnstone L, Hallmark B, Watkins JC, et al. Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation. Nutrients. 2024;16. doi:10.3390/nu16172933
Ahmadi M, Askari VR, Shahri B, Mousavi Noghab SM, Jarahi L, et al. Omega-3 fatty acids effectively mitigate high-sensitivity C-reactive protein (hs-CRP) biomarker of inflammation in acute myocardial infarction patients: a randomized, double-blind, placebo-controlled clinical trial. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:881. doi:10.1007/s00210-024-03330-1
Chen HC, Tai CJ, Huang JY, Kuo TA, Huang YD, et al. Associations of fish oil with cardiovascular disease events: results from the Taiwan longitudinal study in aging. BMC Public Health. 2024;24:1979. doi:10.1186/s12889-024-19512-8
Yu Y, Gao M, Xu H. Ginger Extract and Omega-3 Fatty Acids Supplementation: A Promising Strategy to Improve Diabetic Cardiomyopathy. Physiol Res. 2024;73:351.
Hamaya R, Cook NR, Sesso HD, Buring JE, Manson JE. A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events. Am J Clin Nutr. 2025. doi:10.1016/j.ajcnut.2025.02.028
Kim JY, Kong SYJ, Jung E, Cho YS. Omega-3 Fatty Acids as Potential Predictors of Sudden Cardiac Death and Cardiovascular Mortality: A Systematic Review and Meta-Analysis. J Clin Med. 2024;14. doi:10.3390/jcm14010026
O'Keefe EL, O'Keefe JH, Abuissa H, Metzinger M, Murray E, et al. Omega-3 and Risk of atrial fibrillation: Vagally-mediated double-edged sword. Prog Cardiovasc Dis. 2024. doi:10.1016/j.pcad.2024.11.003
Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. doi:10.3389/fnut.2024.1423228
Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, et al. Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis. Eur J Prev Cardiol. 2025;32:233. doi:10.1093/eurjpc/zwae315
Amangurbanova M, Daher R, Asbeutah AA, Vemuri B, Mirza H, et al. Higher epicardial adipose tissue volume is associated with higher coronary fatty plaque volume and is regulated by waist circumference but not EPA+DHA supplementation. J Clin Lipidol. 2024;18:e773. doi:10.1016/j.jacl.2024.06.006
Lv L, Guo Y, Zheng Z, Li B. Blood metabolites mediate effects of breakfast skipping on heart failure via Mendelian randomization analysis. Sci Rep. 2024;14:18957. doi:10.1038/s41598-024-69874-7
Wang Y, Yang B, Wang C. The association between fatty acids and atherosclerotic diseases: A mendelian randomization study. Clin Nutr ESPEN. 2024;63:447. doi:10.1016/j.clnesp.2024.06.018
Tian S, Guo T, Qian F, Qiu Z, Lu Q, et al. Fish Oil, Plasma n-3 PUFAs, and Risk of Macro- and Microvascular Complications among Individuals with Type 2 Diabetes. J Clin Endocrinol Metab. 2024. doi:10.1210/clinem/dgae482
Asbeutah AA, Daher R, Malik A, Hariri E, Alfaddagh A, et al. The Effect of Eicosapentaenoic and Docosahexaenoic Acid Supplementation on Coronary Artery Calcium Progression in Subjects With Diabetes and Coronary Artery Disease: A Secondary Analysis of a Randomized Trial. Am J Cardiol. 2024;225:98. doi:10.1016/j.amjcard.2024.06.001
Dinu M, Sofi F, Lotti S, Colombini B, Mattioli AV, et al. Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis. Eur J Prev Cardiol. 2024;31:1863. doi:10.1093/eurjpc/zwae184
Braun TS, Drobner T, Kipp K, Kiehntopf M, Schlattmann P, et al. Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study. Nutrients. 2024;16. doi:10.3390/nu16091261
O'Keefe EL, O'Keefe JH, Tintle NL, Westra J, Albuisson L, et al. Circulating Docosahexaenoic Acid and Risk of All-Cause and Cause-Specific Mortality. Mayo Clin Proc. 2024;99:534. doi:10.1016/j.mayocp.2023.11.026
Zeinalabedini M, Ladaninezhad M, Mobarakeh KA, Hoshiar-Rad A, Shekari S, et al. Association of dietary fats with ischemic heart disease (IHD): a case-control study. J Health Popul Nutr. 2024;43:19. doi:10.1186/s41043-023-00489-w
Rennemo J, Berge K, Yousaf MN, Eriksen TB, Welde E, et al. An Atypical Course of Cardiomyopathy Syndrome (CMS) in Farmed Atlantic Salmon () Fed a Clinical Nutrition Diet. Microorganisms. 2023;12. doi:10.3390/microorganisms12010026